Cancers are characterized by a high metabolic heterogeneity allowing cancer cells to survive and proliferate in harsh microenvironmental conditions, including hypoxia, acidosis and limited availability to metabolic resources. In the recent years, a growing body of experimental and clinical evidence has been obtained suggesting that the metabolic plasticity of malignant cells plays a key role in cancer progression.

Indeed, metabolic activities of cancer cells directly influence (epi)genetic modifications, intra- and inter-cellular signaling, metastatic process, immune escape and response of tumors to different anticancer therapies. Recent technical developments have allowed to reveal the spatially- and temporally-resolved complexity of the metabolic networks within tumors and its role in tumor initiation and progression.

The ISCaM2024 symposium is intended to be multidisciplinary with, as a principal aim, the dissemination of the most recent knowledge related to tumor metabolism, with a special focus on the interactions between cancer cells and their microenvironment and on the alterations of the various hallmarks of cancer.

Check https://iscam2024.org/ for more info.