ISCaM2016 - Metabolic Networks in Cancer - Brussels
Wednesday, 26 October 2016 to Saturday, 29 October 2016
- Douglas Hanahan (Lausanne University)
- Pawel Swietach (Oxford University)
- Patrizia Agostinis, Sofia Avnet, Peter Carmeliet, Arkaitz Carracedo, Manel Esteller, Sarah-Maria Fendt, Olivier Feron, Christian Frezza, Peter Friedl, François Fuks, Giuseppe Gasparre, Bob Gillies, Eyal Gottlieb, Marja Jäättela, Nathalie Mazure, Max Mazzone, Carine Michiels, Monica Montopoli, Simone Niclou, Silvia Pastoreková, Jacques Pouysségur, Patricia Renard, Rodrigue Rossignol, Almut Schultze
- Olivier Feron, Carine Michiels, Pierre Sonveaux
Cancers are characterized by a high metabolic heterogeneity allowing cancer cells to survive and proliferate in extreme microenvironmental conditions, including hypoxia, a progressive depletion of metabolic resources, and acidosis. In the recent years, a growing body of experimental and clinical evidence has been obtained suggesting that the metabolic plasticity of malignant cells plays a key role in cancer progression. This metabolic plasticity is central to different networks, not only those directly pertaining to metabolism (including autophagy, cell cannibalism, cooperativity and metabolic commensalism), but also others referring to broader aspects of cancer cell biology, as the metabolic activities of cancer cells directly influences genetic, epigenetic, intra- and inter-cellular signaling and the response of tumors to different anticancer therapies. Consequently, novel therapeutic targets have been identified and new treatments are being developed and/or validated, bringing new hope to selectively target different metabolic determinants that control phenotypes associated to tumor progression. These phenotypes notably include cancer stemness, cancer cell migration and invasiveness, the metastatic process, angiogenesis, and cancer cell resistance to the immune system and to anticancer treatments. The important nature of these recent observations has promoted the nucleation of fundamental scientists and clinicians with a high level of expertise in tumor metabolism within a young international non-for-profit association, the International Society of Cancer Metabolism (ISCaM). The ISCaM2016 symposium is intended to be multidisciplinary, with for major aim to facilitate the exchange of the most recent knowledge related to metabolic networks in cancer between fundamental researchers and clinicians, scientist of international reputation and young investigators, and the experts of the ISCaM and the international scientific community.
The 3rd meeting of the International Society of Cancer Metabolism (ISCaM) will be held at the MCE Congress and Business Center in Brussels, Belgium, on 26-29 October 2016. This 4-day event will address several topics of high interest in cancer metabolism:
- General metabolism & metabolomics
- Amino acid metabolism
- Lipid metabolism
- pH dynamics in cancer
- Microenvironment & Stroma
- Metabolic control of epigenetics
- Metabolic control of stemness & metastasis
The local organizers Olivier Feron, Carine Michiels and Pierre Sonveaux, will be happy to welcome you in Brussels!