Press

Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas

RCC Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas T. Isono, T. Chano, J. Yonese, T. Yuasa Scientific Reports 10 May 2016Renal cell carcinomas (RCC) have two types of cells for carbon metabolism and for… Leggi tutto »Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas

Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism

WE Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism Angela M. Otto Cancer & Metabolism 22 March 2016Virtually everyone working in cancer research is familiar with the “Warburg effect”, i.e., anaerobic glycolysis in the presence… Leggi tutto »Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism

Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism

MET Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism Porporato PE, Payen VL, Baselet B, Sonveaux P Cell Mol. Life Sci. 8 December 2015Metabolic alterations are a hallmark of cancer controlling tumor progression and… Leggi tutto »Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

MET Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway Payen VL, Porporato PE, Baselet B, Sonveaux P Cell Mol. Life Sci. 4 December 2015Metabolic adaptations are intimately associated with changes in cell… Leggi tutto »Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

DLTBOA The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells Pedraz-Cuesta E, Christensen S, Jensen AA, Jensen NF, Bunch L, Romer MU, Brünner N, Stenvang J, Pedersen SF BMC Cancer16 May… Leggi tutto »The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells