paolo.porporato@unito.it

Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism

MET Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism Porporato PE, Payen VL, Baselet B, Sonveaux P Cell Mol. Life Sci. 8 December 2015Metabolic alterations are a hallmark of cancer controlling tumor progression and… Leggi tutto »Metabolic changes associated with tumor metastasis, part 2: mitochondria, lipid and amino acid metabolism

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

MET Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway Payen VL, Porporato PE, Baselet B, Sonveaux P Cell Mol. Life Sci. 4 December 2015Metabolic adaptations are intimately associated with changes in cell… Leggi tutto »Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

DLTBOA The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells Pedraz-Cuesta E, Christensen S, Jensen AA, Jensen NF, Bunch L, Romer MU, Brünner N, Stenvang J, Pedersen SF BMC Cancer16 May… Leggi tutto »The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment

NADH NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment Otto A, Hintermair J, Janzon C J Cell Biochem24 January 2015Characteristic of the tumor microenvironment are fluctuating gradients of reduced nutrient levels and released lactate. A… Leggi tutto »NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

PH Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question Khalid O. Alfarouk, Daniel Verduzco, Cyril Rauch, Abdel Khalig Muddathir, Adil H. H. Bashir, Gamal O. Elhassan, Muntaser E.… Leggi tutto »Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question